Enhancing the effectiveness of industry-academia collaborative development in the region is a common concern of schools, local enterprises, and the prerequisite for promoting this work is to find out the current situation of patent utilization and technology supply and demand between enterprises and universities. Existing patent analysis is mainly concerned about the transfer or licenses, lacking the attention of university-industry cooperation and non-technical factors driving the transfer of patents, whose problem led to a need to improve the identification of the technological needs of enterprises. With the research object of enterprises and universities in Pidu District of Chengdu City, comprehensive patent data and industrial and commercial data reveal the patent utilization status quo and patent technology demand of schools and enterprises in the region, the technological crossroads of schools and enterprises were sort out. Suggestions on regional patent management are put forward based on the comprehensive enterprise demand and regional development orientation.