Turpan City is an important hub of the Silk Road and a historical city, with its rich natural and geographical advantages, has seen the culture and tourism industries play a central role in the economic development of Turpan City in recent years. The pursuit of high quality economic and social development has become more urgent with the implementation of the strategy of rural revitalisation. Taking the ethnic minority settlement area of Turpan City as the research object, the impact of economic and social development in Turpan City is analysed from the perspective of cultural and tourism integration based on the panel data of Turpan City from 2013 to 2022. The results show that the improvement of the degree of cultural and tourism integration can effectively promote the development of Turpan City's economy. Gaochang District, Shanshan County, and Tokon County differ in terms of resource distribution, geographic environment, and level of economic development, and with regard to the regional differences, the effect of the degree of cultural and tourism integration on the economy of Gaochang District is more obvious than that of Shanshan County and Tokon County.