Based on the data of the 11 provinces in the Yangtze River Economic Belt from 2014 to 2022, the development levels of digital logistics and economic resilience were measured. The relationship between the two was analyzed using coupling coordination degree, spatial autocorrelation, and grey relational degree. The research shows that the comprehensive development index of economic resilience is higher than that of digital logistics, but the gap between them is narrowing. As a whole, the degree of coupling coordination has been increasing year by year, and there is a positive spatial correlation. From the perspective of driving factors, the proportion of added value of the tertiary industry has the greatest impact on its coupling coordination degree, and the smallest is the number of internet broadband access. Therefore, it is necessary to promote the coordinated development of digital logistics and economic resilience.