Based on the bibliometric software CiteSpace, the knowledge graph visualization analysis of 1 537 articles on supply chain network optimization sourced from the core library of the Web of Science (WoS) database from 2001 to 2023 was conducted to explore the research overview, hot spots and trends. It is found that there are many researchers and institutions in this field, and Chinese scholars have made significant contributions. The hot topics in this field are robust optimization, facility location, sustainability, etc. The future trend is multi-objective optimization, construction of sustainable supply chains and combine new technologies such as 5G networks, block chain, and artificial intelligence to help supply chain network optimization.