The existing research on the relationship between the heterogeneity of the knowledge structure of executive team (TMT) and corporate performance is controversial, and there is a lack of consideration of the organization's crisis response ability in the performance analysis. In the VUCA environment, organizational resilience is now becoming more and more important, so what is the impact of TMT heterogeneity on organizational resilience? The existing research has not been answered. The relationship and mechanism between the heterogeneity of TMT knowledge structure and organizational resilience was empirically examined by taking the listed companies of software information services (industry code I65) stipulated by the State Securities Regulatory Commission from 2008 to 2022. The results show that the heterogeneity of knowledge structure of TMT can improve organizational resilience, including organizational stability and sales growth ability. The heterogeneity of TMT knowledge structure can improve the organizational resilience of enterprises by improving the attention balance of dual innovation. The heterogeneity of TMT knowledge structure plays a weak role in promoting the balance of dual innovation in enterprises with a higher degree of ownership centralization. The research results can guide enterprises to use the heterogeneity of knowledge structure of TMT team to help enterprises improve organizational resilience, so as to increase their viability in the VUCA environment.