Based on the panel data of 280 prefecture-level cities in China from 2003 to 2021, this paper empirically examines the green innovation effect of undertaking industrial relocation by using multi-period differential method. The regression results show that: according to the benchmark regression model, undertaking industrial transfer has a significant green innovation effect, and the policy effect is sustainable; According to the adjustment effect analysis, the environmental concern of local government positively moderates the promotion effect of undertaking industrial transfer on green innovation ability; According to the heterogeneity analysis, the geographical location and city type of the city have a significant impact on the green innovation effect, and the central region and resource-based city are more conducive to the full play of the green innovation effect. Based on the above conclusions, the policy recommendations include orderly undertaking industrial transfer; focusing on the long-term benefits of national demonstration zones for industrial transfer; Actively release environmental concern signals; To undertake industrial transfer according to local conditions.