The pilot free trade zone is a testing ground for comprehensively deepening reform and expanding opening up, and a gathering place for institutional innovation. In the past 7 years since the establishment of the Henan Pilot Free Trade Zone, it has taken the lead in institutional openness such as management, standards, and rules. The results of institutional innovation are significant, and its supporting role in the industry has become increasingly prominent. However, there are still some gaps and shortcomings in the concept of openness, the institutional mechanisms of management, and the construction of professional talent teams. Under the new situation, the pilot free trade zone should actively connect with the "the Belt and Road", further break through institutional barriers, and effectively boost high-quality economic and social development.