Based on the data of 30 provinces and regions in high-tech industries from 2009 to 2016 to study the impact of high-tech industrial innovation and marketization on economic growth, an empirical test with the dynamic panel GMM estimation and threshold effect test was conducted. The results show that industrial innovation has a negative effect on economic growth in short term, while benefit economicly and socially in long term and overall social walfare. Marketization may have single threshold effect on converge of economic growth may. The weaken effect is larger in the areas higher than threshold compared to areas below to the threshold. The provincial density of robots were applied as the proxy variable to conduct robustness test, and the results also support above conclusions. Finally, relevant suggestions are provided on the practice and policymaking. Future research directions are also discussed.