The spatial information database of national key cultural relics protection units in Shanxi Province is established by ArcGIS software. The spatial analysis method wss used to explore the distribution pattern and time evolution characteristics of cultural heritage in Shanxi Province, and on this basis, the analysis framework of cultural heritage tourism response was constructed.It is found that the spatial distribution of cultural heritage in Shanxi Province is not balanced, and the overall distribution pattern is " 人 " shape. The temporal distribution of cultural heritage in Shanxi Province is uneven, with the largest distribution in the Song and Yuan Dynasties and the least in the Qin and Han Dynasties. The distribution of cultural heritage in Shanxi Province is northeast-southwest in each period, and the center of gravity gradually moves from southwest to northeast. There is a significant positive correlation between cultural heritage and tourism development in Shanxi Province.