Under the new trend of global open and comprehensive economic development, the Chengdu-Chongqing economic circle and Chengdu-Chongqing city cluster are experiencing important transformation opportunities.It aimed to explore how to achieve the coordinated development of the Chengdu-Chongqing airport cluster, promote regional economic integration, and facilitate transportation convenience under the construction of the city economic circle. By analyzing the current development status of the Chengdu-Chongqing cluster, suggestions are put forward to strengthen cooperation among airport clusters, optimize transportation interconnectivity, and enhance international competitiveness. Through coordinated development, the Chengdu-Chongqing airport cluster can generate complementary advantages, improve overall competitiveness, inject new momentum into the development of the city economic circle, and promote the integrated development and sustainable prosperity of the regional economy.