Colleges and universities are an important force for scientific and technological innovation in China. The industrialization of achievements is the core link between scientific research and industry. It has the dual significance of supporting economic development and feeding back scientific research. However, it’s a complex process of transforming science and technology into economy. It is the optimal solution of economic factors such as investment, time and risk. Starting from the development process of science and technology and industry after reform and opening-up, the evolution process of the industrialization of achievements was analyzed, surface and deep-level factors that restricted the industrialization of achievements were put forward, the definition and internal laws of industrialization of scientific and technological achievements in universities were studied,related discussions were conducted and relevant suggestions were put forward for promoting the industrialization of scientific and technological achievements.