The Kurdish Region of Iraq is located in the northern folded zone of the Zagros Basin, where oil and gas resources are abundant. In recent years, there has been little study of the exploration potential in this region. The article utilizes previous research results and the latest data from foreign databases to study the conditions and factors of oil and gas accumulation in this area, and studies its exploration potential targets. The research results indicate that: Among the four sets of oil and gas systems developed in the Iraq reservoir area, the Jurassic and Cretaceous one is the main oil and gas systems. Oil and gas are mainly distributed in the Kirkuk low fold belt. The main controlling factors of oil and gas enrichment are high-quality regional cap rocks, the distribution of effective Source rock and the later tectonic movement.The most promising reservoir formation combination for exploration is the Triassic in the northern low fold zone, the Jurassic low gentle anticline trap, and the reservoir formation combination in the footwall of the fault.