In order to explore the problems of scientific and technological talent policy in Nanjing, the policy text analysis method is used to compare and analyze the science and technology talent policy texts of Nanjing and Shenzhen, Hangzhou and Suzhou from 2007 to 2022. The study found that in terms of time trend, the number of scientific and technological talent policies in Nanjing tends to increase over time. In terms of the use of policy tools,the distribution of the use of various policy tools in Nanjing is relatively unbalanced,and supply-oriented policies are dominant.The effect of some policies is not obvious due to slightly weaker support or lacking of policies. Finally, further forward suggestions are put on optimizing Nanjing science and technology talents policy from four aspects:highlighting the differences in policies, making policies more precise, optimizing the distribution balance of policies and enhancing the effectiveness of policies.