Original innovation has the characteristics of originality, exploration and breakthrough, which is an important means to solve the problem of "bottleneck" in science and technology, and also an important strategy to promote Chinese science and technology selfreliance and realize Chinese modernization. Relying on original innovation and core technology breakthrough, China's ultra-high pressure technology and industry continue to gain global competitive advantages in the market, and gradually grow into the "created in China" model. Based on the innovation breakthrough case of TBEA, a key core technology supplier in the UHV industry, how the enterprise implements the original innovation strategy under the background of the national innovation strategy of UHV was analyzed, and the key core technology breakthrough from 0 to 1 was achieved. Research has important implications for promoting original innovation in complex equipment industry and cultivating more specialized new enterprises.