Landslide, as a typical geological disaster, exists widely in southwest China. Especially in the southwest hilly area, landslides are quite frequent. When engineering construction is carried out within the scope of landslide, the influence of landslide on engineering needs to be considered. Based on an engineering case located in Yunnan Province,the stability is analyzed of the slope within the landslide range of construction land, considering the stability of the slope with the largest height difference under different working conditions, so as to put forward the treatment measures of the slope within the landslide range of construction land. The results show that the overall stability of landslide in engineering cases is good, and it is in a critical stable state under earthquake conditions, but local deformation and failure may occur under load, rainstorm and earthquake conditions. After taking anti-slide pile and other engineering treatment measures, the site is stable and meets the requirements of construction land in town. The research results can provide reference for similar engineering construction.