The current situation and problems existing are analyzed in the output and development of science and technology finance and incubation carriers in the east and northwest of Guangdong.The influencing factors and development modes of the integrated development of science and technology finance and incubation carriers, are studied. Four modes are proposed according to the enterprise life cycle growth theory, the characteristics of the integrated development of various science and technology finance carriers and the role played by various financial subjects: incubation and cultivation seed guidance type, including incubation leading financial combination type Incubation accelerated financial integration type and incubation assisted capital driven type. Then the countermeasures and suggestions of science and technology finance are put forward to promote the high-quality development of science and technology entrepreneurship incubation carrier in east and northwest Guangdong.