With the advancement of industrialization, the boundary between manufacturing and producer services continues to extend. Giving full play to their synergistic agglomeration effect has become the key to promote industrial integration. Through the location entropy method, the collaborative agglomeration index of manufacturing and producer services in Hunan Province are constructed, the temporal and spatial differentiation characteristics of industrial collaborative agglomeration in Hunan Province are discussed , and the following conclusions are proposed: there are regional differences in the level of collaborative agglomeration of manufacturing and producer services, and presents the form of collaborative agglomeration centered on Changsha-Zhuzhou-Xiangtan(Chang-Zhu-Tan)urban agglomeration.