Based on the three dimensions of infrastructure, transaction scale and development potential, the provincial panel data from 2013 to 2019 was selected to set a comprehensive index evaluation system for the development level of e-commerce, the comprehensive index of the development level of e-commerce and its three dimensions index were calculated by using the entropy method, and the regional heterogeneity analysis was carried out. The results show that the comprehensive index of e-commerce development level show an upward trend, and through the analysis of regional heterogeneity, the development level of e-commerce in eastern China is significantly higher than that of other regions, and the development potential of e-commerce is relatively large in terms of the three dimensions.