Abstract:273 employees were surveyed using psychosocial security climate scale PSC-12, work autonomy scale, job satisfaction scale and turnover intention scale, and the chain mediating effect of work autonomy and job satisfaction on psychosocial safety climate and turnover intention was investigated. The results show that : Job autonomy and job satisfaction play the role of chain mediators in psychosocial safety climate and turnover intention.In the chain mediation model of psychosocial safety climate→work autonomy → job satisfaction → turnover intention, all the other path coefficients are significant except the coefficient of the path from work autonomy to turnover intention. It can be seen from this that the organization's attention and attention to employees' mental health can effectively improve their work autonomy and job satisfaction, thus reducing their turnover intention.