The development imbalance among airports in multi-airport region is serious, and small and medium-sized airports rely on government subsidies to survive for a long time. Increasing the market share and revenue of small and medium-sized airports, thereby enhancing their competitiveness, is an effective way to improve the uneven development between airports in many airport regions. By modeling a single airport, it is found that when low-cost airlines dominate, the airport's profits are maximized when the share of airlines within the airport is not equal. Then the Hotelling model of the two airports was established, and the it is found that small and medium-sized airports working with low-cost airlines can reduce air fares and increase the throughput of small and medium-sized airports, thus improving the imbalance in the development of airports in multiple airport regions. Finally, by using Rubenstein's "bargaining model" of the airport and the Division of aviation cooperation benefit-sharing mechanism, it is found that the airport and the internal airlines to form a strategic alliance to bring residual profits, the two in the sharing of this residual profit is the most advantageous countermeasure is to improve their own patience, so that not only to maintain a long-term strategic alliance, and ultimately can also share the remaining profits.