In order to systematically and scientifically compare and analyze the research status of international and domestic prefabricated building construction safety, and find the blank of the industry, 345 related literatures from Web of Science and CNKI database were measured and visualized by using CiteSpace, and the key words cluster map, the core authors and co-cited literatures cluster map, research time zone map and so on were drawn. The results show that: in recent years, the research literature on the construction safety of prefabricated buildings in China and other countries is on the rise. Through clustering and word frequency analysis, we can see that the research on construction safety of domestic and overseas prefabricated buildings involves "safety management" and "BIM technology"; With regard to research hotspots, foreign scholars focus on the application of "offsite construction" ,"composite structure" and "iots", while domestic scholars establish some safety management systems through the research methods such as "analytic hierarchy process" and "fuzzy comprehensive evaluation"; By analyzing the core authors, it is found that foreign scholars communicate closely and have formed a stable cooperation network, while domestic scholars mainly study independently and have not yet formed a stable research network; With regard to research trends, foreign scholars pay more attention to the combination of prefabricated building safety related theories and engineering practice, while domestic scholars focus on theoretical research, methods and experience summary. Based on the above comparative analysis results, the paper puts forward countermeasures and suggestions to promote the scientific development of prefabricated building construction safety in China. The research results of will provide relevant reference for the research and further development of prefabricated building construction safety in China.