Innovation policy is the externalization of government intention and behavior orientation, the coordination of policymakers and policy measures can explain the interdepartmental collaboration. Based on 712 innovation policy texts written by various departments of the State Council of China from 2013 to 2018, the cooperation network of policymakers is drawn annually. From dimensions of supply side, demand side and environment side, quantifies innovation policy is measured. And the coordination degree of policy measures among departments is calculated. From these data, the research analyzes the cooperation status after the implementation of innovation-driven development strategy of main innovation policymakers quantitatively. The results show that the MOST, the MIIT, the NDRC and the MOF have formed a core cooperation relationship in the practice of innovation policies. The MOST and the NDRC occupy a dominant position in the cooperation network. Inter-ministerial cooperation can improve the imbalance in the application of policy measures by a single department, but the effect is not yet obvious in the practice of innovation policies in China. Differences in the coordination of policy measures among departments are jointly affected by the scope of departmental responsibilities and political pressure from the central government.