China's high-speed railways are currently in a period of rapid development. The construction of high-speed railways has strengthened the economic exchanges and industrial links between various regions. Based on the data of 17 prefecture-level cities in Henan Province from 2005 to 2018, combines the construction of high-speed rail with the agglomeration of producer services, and the agglomeration of producer services under the influence of the opening of high-speed railways and regional economic growth. An empirical model of the impact of high-speed rail construction on the agglomeration of producer services is constructed; and the role and magnitude of the impact of the agglomeration of producer services under the influence of high-speed railways on regional economic growth are further explored. Using the PSM-DID method to conduct an empirical test, and concludes that the development of high-speed railways has a positive impact on the agglomeration of regional producer services, and the agglomeration of producer services under the influence of high-speed railways significantly promotes regional economic growth.