With the complex changes in the international and domestic political pattern and the uncertainty of the global supply chain, China's economic growth is driven by domestic demand and consumption. It is imperative to optimize the bilateral pattern of supply and demand in the domestic market, give full play to the advantages of China's market scale and market capacity, and build a new dual cycle development pattern. Based on the comparative study of China's three interregional economic development levels, the paper holds that there are great differences in the economic development between the East, the West and the East. The level of urbanization helps to enhance the level of economic development. The two interregional regions have large market space and development potential, which is an important reform focus of coordinated economic development. High quality coordinated development should start from promoting interregional coordination mechanism and industrial optimization In order to promote the prosperity and development of regional economy, we should integrate resources quickly, speed up the layout of double cycle development.