The integration of industry and education is the inherent requirement of high quality development of vocational education. Through grounded theory, explores the influencing factors and internal mechanism of the integration ecosystem of industry and education.It is found that the dynamic stability of the ecosystem is affected by the subject system and the environmental system.The subject system is the metaphor of the ecological community of the integration of production and education, including four ecological factors of students, enterprises, schools and governments. Students are core niche of the whole system. Environmental system is a metaphor of the ecological environment of the integration of production and education, including four environmental factors: market, region, technology and culture.It is proposed to provide guarantee for the system operation by clarifying the top-level design idea, enhancing the willingness of the school and enterprise to participate, constructing the win-win service system and innovating the talent training mode. The research provides theoretical basis and practical reference for the integration of industry and education.