Talent is the most critical factor of scientific and technological innovation. Based on ‘China Statistics Yearbook on High Technology Industry’ and ‘China Statistics Yearbook on science and technology’, this paper has compared Jiangsu’ s main talent indicators with those of Guangdong and Zhejiang, in order to find out the advantages and disadvantages of the development of Jiangsu’s sci-tech talents. This paper has pointed out that there are some problems in Jiangsu, such as slow growth of R&D personnel, shortage of basic research talents, and unbalanced regional distribution of talents. In addition, this paper has explored the deep reasons of these problems, and putted forward some countermeasures and suggestions, such as strengthening the agglomeration effect of talents in high-tech industry, building a team of high-level basic research talents, and improving the ability to attract and cultivate talents in the Middle and North of Jiangsu.