Ningxia plans to create a national independent innovation demonstration zones, which is of great significance for enhancing regional innovation capabilities, supporting the ecological protection of the Yellow River Basin and the construction of high-quality development pilot zones.This article gives a brief SWOT analysis based on this background，It illustrates the strengths and the weakness of the Scientific and technological innovation and development in Ningxia. The impartial judgments of the opportunities and threats of national independent innovation demonstration zones in Ningxia.Proposed the general idea, strategic positioning and path suggestions of constructing national independent innovation demonstration zones.