With the acceleration of industrialization in China,the contradiction among industrial economy,ecology and industrial structure is becoming more and more prominent.Constructing industrial economy and economy comprehensive evaluation index,and using the method of entropy method,coupling coordination degree function modeling method and industrial structure index are used to analyze the relationship between industrial structure and the coupling coordination of Economy-Ecological in the prefecture-level cities in Jiangsu Province.The results showed that:industrial economy and economy comprehensive development level and the degree of coordinated development generally increased,while the upward trend of some cities is not obvious,or even shows a downward trend from 2012 to 2016;the relationship between industrial structure and coordination is generally not obvious,but the change of industrial structure and coordination exists.