Innovation plays a vital role in the development of high-tech and high-input biomedical industry.Based on the theory of innovative ecosystem and referred to the natural ecosystem, the model of biomedical innovative ecosystem is established. Causal diagram and stock-flow diagrams are depicted by using the method of system. And the factors that affect the development of biomedical innovative are analyzed. Based on this, suggestions are put forward for the construction and development of biomedical innovative ecosystem, such as perfecting government policies, improving independent innovation capability, increasing the cooperation degree of industry, university and research, and paying attention to the management, application and protection of intellectual property rights.