China has identified 34 culture and technology integration demonstration bases. It aims to strengthen the integration of cultural science and technology, continuously cultivate a new format of culture industry and promote the sustainable and healthy development of the cultural industry. Through the investigation and inspection of bases in Yangtze River Delta and the information published on the base, the author summarizes and analyzes the development status and existing problems of the national cultural and technology integration demonstration bases in Yangtze River Delta, and puts forward some suggestions. In order to provide useful reference for the base's follow-up development.