The conversion of new and old kinetic energy was an important measure to achieve a healthy and sustainable economic development. The key to promoting the conversion of new and old kinetic energy relies on scientific and technological innovation. Science and technology are the long-term driving forces for the conversion of new and old kinetic energy. On the basis of analyzing the connotation and dialectical relationship between science and technology innovation drive and new and old kinetic energy conversion, this paper analyzed the function of science and technology innovation driving the conversion of new and old kinetic energy, and emphatically elaborates the four new promoting four modernizations, deepening supply side structural reform, Scientific and technological innovation, strong talent on the conversion of new and old kinetic energy lead, stimulate, upgrade and support role. The purpose of this paper was to provide reference for the development ideas that were driven by science and technology innovation and promote the conversion of new and old kinetic energy, and put forward reasonable countermeasures and suggestions from the perspective of scientific and technological innovation support.