Deepening the cooperation between local and central enterprises can promote the two sides to play their advantages, cooperate with each other, achieve mutual benefit and win-win cooperation and develop hand in hand. Under the new era, the cooperation between local and central enterprises shows that the demand of local governments is increasingly strong, the scale of investment of central enterprises is expanding day by day, and the central enterprises and local cooperation are becoming more rational. At the same time, it is also facing the pressures and challenges brought about by the expansion of overseas investment by central enterprises, the weakening of local investment temptation and the cooperation of the central region into the “run-in period”. For this reason, the local government has created a new mode of docking cooperation in termsofmacroeconomic regulation, industrial layout, military-civilian integration, strategic investment, etc. And the local government has changed the development concept, explored the negotiation decision-making mechanism, improved the level of public services and improved the work guarantee mechanism to promote the smooth implementation of local and central enterprise docking cooperation projects.