The spatial-temporal pattern and coupling relationship between industrial output and pollutant emissions in Henan Province were analyzed using GeoDa spatio-temporal analysis and decoupling index. The factors and contribution of industrial pollution emission in Henan Province were discussed using Kaya equation and LMDI factor decomposition method. The research shows that:①Various types of industrial pollution are relatively serious in western Henan and northern Henan, and local cities should carry out targeted pollution control and emission reduction;②Industrial structure optimization and emission intensity reduction can reduce industrial pollutants The increase in the scale of output value and the increase in the proportion of pollutant source industries are positively driving the emission of industrial pollutants.