The popularity of smart phones make health APP widely be used, but there is a general phenomenon that health APP is not used very frequently after be downloaded. So to analysis the factors influencing Continuance Intention of Health APP is very necessary. Based on relevant literatures of health APP and IS continuance usage, considering the characteristics of health APP users’ behaviors, this paper adds eHealth literacy into ECM-IS and constructs health APP continuance usage model, to analysis the mechanism of eHealth literacy and confirm impact on continuance intention. Meanwhile, this paper gives definitions of variables and theoretical hypotheses of the model and lays the foundation for empirical research in the future.