Quanzhou City of Fujian Province is a national comprehensive reform pilot city. In the construction of urbanization, it has formed its own unique mode of development, and promoted regional economic development. However, there are still some deep-seated contradictions and problems in the process of urbanization in Quanzhou City. This paper makes an empirical study on the urbanization and regional economic growth, urbanization and adjustment of industrial structure, urbanization and employment and other aspects, and puts forward the corresponding countermeasures and suggestions, hoping to provide reference for the construction of regional and national towns.