Railway enterprise faces all kinds of opportunities and challenges when developing e-business in the background of internet +. Building up e-business platform and promoting the intergrating of railway enterprise and internet is the best way to reply the challenges. Therefore, railway enterprise should make a clear development target, bulid up e-business platform, innovate the strategy, expand the service scope, and optimize allocation of resources. In order to develop railway e-business, railway enterprise should suppy more customized service and make the price much more flexible.