Based on the data of urbanization and industrial structure development in Shangluo from 1979 to 2015, this paper studies the development and interaction between industrial structure evolution and urbanization process by using the SPSS software analysis method, and obtains the correlation between them. Impact mode. The results show that the industrial structure of Shangluo is irrational, the development speed of urbanization is slow, and the development of industrial structure and urbanization is not in harmony. On this basis, the author puts forward some countermeasures and suggestions on the problems existing in the industrial structure and urbanization.