The research focus on its influence on the price of commercial residential building from the aspect of the properties of commercial residential building for the first time. First of all, it proves the existence of long-term equilibrium relationship among factors that are sales and price of the real estate, residents' disposable incomes, and interest rates by panel co-integration testing, and builds a long-term demand model by applying the variable coefficient model. Secondly, it makes use of the panel data of the Yangtze River Delta and long-term demand model to figure out the properties of commercial residential buildings in the region of the Yangtze River Delta. It concludes that commercial residential buildings in Jiangsu Province, Shanghai and Zhejiang Province are normal goods, inferior goods and Giffen goods respectively. As thus, aiming at the different properties of commercial residential buildings in these three regions, this paper comes up with several specific measures and suggestions, such as restricting home-purchase, increasing residents’disposable income while restricting home-purchase, expanding investment channels, and government giving signals of reasonable house prices to citizens. The outcome of this study will better adjust the high prices state of the real estate market to the government’s expectation.