With the advent of the fourth industrial transfer，the industry in developed countries and China's coastal areas are rapidly transferred to internal areas of China. So,Changsha will face an important problem that how to selectively undertake industry transfer. To analyze related indicators of Changsha large and medium-sized enterprises above designated size in 2015. using principal component analysis, calculate the index of competitive advantage, and chose the manufacturing sector, special equipment manufacturing industry, biological medicine, tobacco products and so on as a developing industry in the future, in order to promote industrial upgrading and achieve the rapid growth.