As the most active factor within the organization, employee plays a critical role in the successful implementation of knowledge management. With taking Microsoft Corporation as a case study object, this paper researched on the Human Resource Business Intelligence method, the talent training and development plan as well as the innovation incentives in Microsoft's Human resource planning, and then analyzed how the human resource planning reduces organizational knowledge loss and integrates the basic process of knowledge management. Finally, based on the reference of Microsoft Corporation’s advanced experience, this report provides some useful suggestions for other organization in human resource planning.