The credit rating agency is not only an important part of the development of science and technology financial intermediaries, but also an important booster of the development on technology industry. The paper takes latest stock pool of CNI Z 50 INDEX as the object of study, using factor analysis, principal component analysis, K-means clustering analysis method, listing Z score model and credit rating standards of science and technology enterprise under the perspective of financial innovation, validating the effectiveness of Z score model in the latest stock pool of Shen Zhen science and technology 100 Index.it is found that the Z model of the listed companies in the paper has some reference, but it is not persistent.