Recently,economic development of Jilin has achieved rapid development,but, unbalance of regional economy development is a prominent problem in the social-economic development status of Jilin province,in the article, raises an appropriate quota system to measure regional economic development, on this basis, combination with factor analysis in Multivariate Statisticas, to make comprehensive estimation for economic development of 9 major cities,and explores the characteristic of social-economic development status of Jilin province, give some suggestions on the implementation of the balanced economic development forward.