Manufacturing Competitiveness for regional economy has a crucial supporting role. Through establish MCI (Manufacturing Competitiveness Index) model to quantify, it can be found that Zhejiang manufacturing competitiveness and competitive advantage significantly weakened in recent years with increased labor costs. To accelerate the innovation-driven, talent-driven, technology-driven, reform-driven, to improve labor productivity and promote industrial restructuring and upgrading, to enhance the industry's core competitiveness and create economic upgrade, to achieve long-term sustainable growth in the future, etc. these are Zhejiang economic main tasks throughout the long period of time.