This paper calculates the total factor productivity of the Yangtze River Delta Region's Industry from 1998 to 2011 by DEA-Malmquist, divides the 25 industries into high-tfp industries, middle-tfp industries and low-tfp industries. Studies have shown that, the average growth rate of Total Factor Productivity in Yangtze River Delta Region's Industry, during the years between 1998 and 20011 is 9.3% and the main source of Total Factor Productivity growth is technological progress. Technical efficiency is the most eminent factor to separate the 3 sorts of industries. Low-tfp industries accounted for a heavy proportion of Industrial output, is the focus of future work.