Talents,?especially high-quality?technological talents is?an important engine of economic?and social development,?is the focus of the competition among countries and regions. This paper first summarizes the research status of technological talents and its aggregation, and then it references model of the population and designs the aggregation model of technological talents, basing on the liquidity and aggregation of technological talents. Finally, taking cross section data of 16 cities in Anhui Province as an example for empirical analysis, it calculates the technological talents aggregation degree , analyzes the relationship between the gathered technological talents and the economic development, and puts forward relevant thinking and policy suggestions. Research shows that technological talents aggregation and regional economic development in Anhui Province presents a significant positively related linear relationship.