At present, promoting the development of strategic emerging industries has become an important duty of the construction of the West Coast Strait Economic Zone. As university is an important place for fostering talents, it plays an important role in meeting the needs of strategic emerging industries’ talents in the West Coast Strait, cultivating innovative entrepreneurial talents of technology. Fuzhou University has some opportunities and threats in cultivating Innovative and entrepreneurial talents. In recent years, Fuzhou University has gained a lot in the reformation of Innovative and entrepreneurial talents cultivating model, but it is also confronted with some difficulties. It is essential for Fuzhou University to accelerate reformation of Innovative and entrepreneurial talents cultivating model from the angle of teachers developing, major construction, experimental class, talents cultivating program, practicing teaching basis, safeguarding mechanism, Innovative and entrepreneurial training program management and interschool cooperation, so as to accelerate the development of strategic emerging industries in the West Coast Strait Economic Zone.