Innovative system paradigm is the core of technology innovation research. Watching from the development, it has undergone five stages of corporate innovation system, the national innovation systems, regional innovation systems, industrial innovation system, innovation ecosystem, which are interrelated and different. mutually. By comparison and analysis, including the comparison between the national innovation system, regional innovation systems and industrial innovation system, as well as the innovation ecosystem research and innovation system, on the one hand, allows people to better identify them, and to grasp the essential characteristics of each paradigm; On the other hand, it is possible to more clearly understand the current research status and deficiencies ,and to determine future research directions.