The economic and trade cooperation has achieved great development between China and South Korea since the establishment of diplomatic relations. Qingdao, as the frontier cities of China's foreign trade, has a closer trade relation with South Korea. Because human activities are always constrained by the scarcity of resources, the behavior of a particular economic subject has an important of impact to the behavior of other economic entities and their expected in the limited distribution of benefits. They also choose their own behavior-based strategy as a basis of the expected of other economic entities. The “Game” has formed with the process of mutual selection strategy. This article is on how to further deepen economic and trade cooperation between Qingdao and South Korea and use the “game theory “in depth research.