Water blocking damage is a common issue in the development of tight sandstone gas reservoirs, significantly impacting gas well production and reservoir recovery rates. Taking the gas reservoirs in the southern margin of Ordos as an example, the degree of water blocking damage in the gas reservoirs was analyzed, the typical production characteristics of gas wells with water blocking damage in tight gas reservoirs was discussed, and technologies were proposed for the prevention and treatment of reservoir water blocking. The research results indicate that the gas reservoirs in the southern margin of Ordos experience moderate to strong water blocking damage. After water blocking, gas wells exhibit production characteristics such as insignificant production increase after fracturing, inability to restore production after reopening the well following shutdown, and limited effectiveness of wellbore drainage measures. To effectively prevent and treat water blocking damage, comprehensive prevention and treatment methods are proposed, including the use of small-diameter coiled tubing to avoid premature fluid accumulation in gas wells, maintaining continuous and stable production, and implementing physicochemical processes to eliminate water blocking damage. Field test results demonstrate that the integrated application of these methods can effectively prevent and eliminate water blocking damage, thereby restoring gas well production.