Faced with the increasing uncertainty risks and the complex world situation, more and more enterprises are seeking to build diversified supply chain channels and marketing strategies. Taking two clothing companies, Hailan Home and Boohoo, as examples, their supply chain channel selection strategies and operational status were analyzed based on the Supply Chain Operation Reference Model (SCOR), and the reasons for such differences were explored. Finally, through analysis and discussion, strategies such as focusing on customer characteristics and segmenting the market, utilizing RFID technology, and providing door-to-door logistics are proposed to provide reference and guidance for clothing enterprises to optimize their supply chain channels.